Sistem de calcul a starii fatului si riscului de aneuploidii

Rules according to the Confidetial enquiry into Stillbirths and Deaths in infancy (UK) Programme written by DJR Hutchon copyright. Translation by Razvan Socolov MD PhD Iasi- Romania. Requires Internet Explorer 4.0 or above (or eqivalent) for calculator to work. Year 2000 compliant. If Serum screen or nuchal thickness not available, (or less than 1 mm) leave blank. Only valid for calculating Down risk for CRL 38 - 84mm These calculations assume that the NT measurements are made using the same protocol as the Fetal Medicine Foundation. Instructions for using OFFLINE

CRL dupa formula Smith et al REFERENCES  data in forma date/month/year (4 digits for year)
  ie month/date/year (4 digits for year)
Nume pacienta Data nasterii Printer friendly version
Data UM Sigur (Y/N)? Yes - - - ciclul normal Implicit 31 zile (see ref Bergsjol et al)
Data ecografie Pliu nucal mm. MoM= Risc Down -screening seric 1/
CRL în mm mm sau BPD mm mm (INTRODU UNA SINGURA) corespunde la sapt + zile
Frecventa cardiaca fetala in momentul ecografiei a fost /min
Ref Riscul legat de varsta de sindrom Down (DS) la nastere 1/ Riscul integrat de DS la nastere 1/
RefRiscul legat de vârsta pentru DS la momentul ecografiei 1/ Riscul integrat - momentul ecogf 1/ (include FCard daca e introdusa)
DPN dup? UM dupa ecogf 42 sapt la
DPN cel mai corect este
Declansarea nasterii nu se rcomanda inainte de 14% risk of labour before this date.
Trisomie 18 risc la 9-14 sapt= 1 in la 15-20 sapt= 1 in in la nastere= 1 in
Trisomie 13 risc la 9-14 sapt= 1 in la 15-20 sapt= 1 in in la nastere= 1 in
Gestation by scan on date is wks +days.

Evaluarea starii fatului - sistem expert

Introdu data ecografiei, masuratori, IAmn si IR ombilical daca sunt disponibile

Prima || A doua || A treia Normal
ecografiei Z || ecografiei Z || ecografiei Z +1.645 to
Data scor || Data scor || Data scor -1.645
HC || HC || HC
AC || AC || AC
FL || FL || FL
Sarcina sapt || sapt || sapt
G fetala estim Kg || Kg || Kg
IR Ombil
I Amn

Zona normala a scorului Z e -1.645 la +1.645. Daca exista doar doua masuratori, introdu amanuntele în a doua si a treia coloana. Normal range for Z score is -1.645 to +1.645. This calculator is for educational use. It is believed accurate but no responsibility for accuracy of the results is accepted by the author. David J R Hutchon BSc, MB, ChB, FRCOG Consultant Obstetrician, Memorial Hospital, Darlington, England. Hot FindReturn to calculator 
Go to paper on proposal for valid customised charts generation ("Back to the future for Hermanni Boerhaave" published by OBGYN.NET)

Comments and suggestions are welcome and will be included in the comments section.


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This page's count says this page has been visited  times since 23rd May 1999. All my calculators will work OFF-LINE if you wish. Instructions for use OFF-LINE You are welcome to copy them over. But check for updates from time to time!


BMJ article on publishing raw data and real time statistical analysis on e-journals

Demonstation of raw data and real time statistical analysis

Northern Region Fetal/Maternal Medicne Special Interest Group Guidelines
Fetal medicine Unit, St Georges, London        Joseph Woo's Ultrasound       The
Correct application of Bayes theorem in estimating sequnetial conditional risk

1. Hutchon DJR. Customised ultrasound dating charts. British Maternal and Fetal Medicine Society. fourth Annual Conference, University of York. Abstartcs - Journal of Obstetrics and Gynaecology 1999 19:suppl 1;s57
2. Hutchon DJR. Routine ultrasound is the method of choice for dating pregnancy. Br J Obstet Gynaecol 1999:106;616
3. Hutchon DJ, et al. Clinical interpretation of ultrasound biometry for dating and for assessment of fetal growth using a wheel and chart: is it sufficiently accurate? Ultrasound Obstet Gynecol. 1999 Feb;13(2):103-6. Copyright 1999, DJR Hutchon. Restricted use is hereby granted (personal OK) so long as this code is not *directly* sold and the copyright notice is buried somewhere deep in your HTML document.
Smith GCS, Smith MFS, McNay MB and Flemming JEE First-trimester growth and the risk of low birth weight New England Journal of Medicine 1998;339:1817-22

Kurmanavicius J, Wright EM, Royston P, Zimmermann R, Huch R, Huch A, Wisser J. Fetal ultrasound Biometry: 1. Head reference values. British Journal of Obstetrics and Gynaecology. 1999 106:126-135
Kurmanavicius J, Wright EM, Royston P, Zimmermann R, Huch R, Huch A, Wisser J. Fetal ultrasound Biometry: 2. Abdomen and femur length reference values. British Journal of Obstetrics and Gynaecology. 1999 106:136-143
Bergsjo P, Denman III D W, Hoffman H J, Meirik O. Duration of human singleton pregnancy - a population based study. Acta Obstet Gynecol Scand 1990;69:197-207
Altman D G and Chitty L S. New cahrts for ultrasound dating of pregnancy Ultrasound Obstet Gynecol 10 (1997) 174 - 191
Moore T R and Cayle J E. The amniotic fluid index in normal human pregnancy. American Journal of Obstetrics and Gynecology 1990;162:1168-73
Cuckle H S, & Schmi I Calculating correct Down's syndrome risks. British Journal of Obstetrics and Gynaecology 1999;106:371-372
Wald N J, Watt H C, & Hackshaw A K. Integrated screening for Down's Syndrome based on tests performed during the first and second trimester The New England Journal of Medicine 1999;341(7):461-467
Pandya P P, Johnson S, Malligianis P, and Nicolaides K H. First Trimester fetal nuchal translucency and screening for chromosomal abnormalities. Ultrasound and early pregnancy Chapter 7
Cuckle H S, Wald N J, Thompson S G. Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol (1987) 94:387-402
Snijders R J M, Holzgreve W, Cuckle H and Nicolaides K H. Maternal age-specific risks for trisomies at 9-14 weeks gestation. Prenatal Diagnosis (1994) 13:543-552 For the purposes of the calculator I have assumed a uniform loss of pregnancy as a result to miscarriage between 9 and 14 weeks and 15 and 20 weeks.
Zosmer N, Souter V L, Chan C S Y, Huggon I C and Nicolaides K H. Early diagnosis of major cardiac defects in chromosomally normal fetuses with increased nuchal translucency. Brtish Journal of Obstetrics and Gynaecology 1999;106:829-833
Morrison J J, Rennie J M, & Milton P J. Neonatal respiratory morbitiy and mode of delivery at term: influence of timing of elective caesarean section. British Jouranl of Obstetrics and Gynaecology 1995 102 101-106
Madar J, Richmond S & Hey E. surfactant deficient respiratory distress after elective delivery at 'term'. Northern Region Maternity Survey Meeting 1999. Accepted for publication in Acta Paediatrica
Hyett J A, Noble P L, Snijders R J M, Montenegro N, & Nicolaides K H. Fetal heart rate in trisomy 21 and other chromosomal abnormalities at 10 - 14 weeks of gestation. Ultrasound Obstet Gynecol 7 (1996) 239-244
I am grateful to Professor Howard Cuckle for information on the Gaussian LR equation for a single variable.
This risk assumes no previous affected pregnancy. A previous affected pregnancy increases the risk further, to about 1 in 200 at age 30 and 1 in 25 at age 45.
The maternal age specific incidence of trisomy 21 at birth is 54% lower than at 9-14 weeks of gestation.


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